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Tofacitinib 5 mg Tablet — IEB Pharmacy

Tofacitinib 5 mg tablets (sold under different brand names depending on where you are) treat certain inflammatory and immune-related diseases. It’s a prescription drug, part of a group called Janus kinase (JAK) inhibitors, which basically dial down an overactive immune system. What is Tofacitinib? Tofacitinib is a small molecule drug that messes with specific signaling pathways in immune cells. You take it as a tablet. Usually, doctors turn to it if other meds haven’t worked or if someone can’t tolerate those other options. The “5 mg” just refers to how much medicine is in each tablet. Researchers first developed the Tofacitinib 5 mg tablet while studying autoimmune diseases—those are the conditions where your immune system turns against your own body, causing damage and inflammation, like in your joints or gut. Tofacitinib helps slow this misguided attack, so inflammation, pain, and tissue damage can calm down over time. How does it work? Inside your cells are enzymes called Janus ki...
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Baricitinib 4 mg (Barigen) | IEB Pharmacy

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Baricit 4 mg is indicated for the treatment of adult patients with moderate to severely active rheumatoid arthritis who have had an inadequate response to one or more tumor necrosis factor (TNF) antagonist therapies. Limitation of Use: Use of Baricit 4 mg in combination with other JAK inhibitors ... Read more: Baricit 4 mg is indicated for the treatment of adult patients with moderate to severely active rheumatoid arthritis who have had an inadequate response to one or more tumor necrosis factor (TNF) antagonist therapies. Limitation of Use: Use of Baricit 4 mg in combination with other JAK inhibitors, biologic DMARDs, or potent immunosuppressants such as azathioprine and cyclosporine is not recommended. Therapeutic Class Immunosuppressant Pharmacology Baricit 4 mg is a Janus kinase (JAK) inhibitor. JAKs are intracellular enzymes that transmit signals arising from cytokine or growth factor-receptor interactions on the cellular membrane to influence cellular processes of hematopoiesis a...
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